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Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors
Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-physiological contexts (myopathies, atrophy, aging) FAPs cause fibrotic and fat infiltrations that impair muscle function...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7093513/ https://ncbi.nlm.nih.gov/pubmed/32210313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-62194-6 |
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