Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased Lethality

Background: Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA-editing enzyme that is involved in several functions including the deamination of adenosine to inosine, RNA interference (RNAi) mechanisms and microRNA (miRNA) processing, rendering ADAR1 essential for life. Methods and...

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Detalhes bibliográficos
Publicado no:Front Cardiovasc Med
Main Authors: el Azzouzi, Hamid, Vilaça, Andreia P., Feyen, Dries A. M., Gommans, Willemijn M., de Weger, Roel A., Doevendans, Pieter A. F., Sluijter, Joost P. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cardiovascular Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093378/
https://ncbi.nlm.nih.gov/pubmed/32258062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2020.00030
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