Will iPSC-cardiomyocytes revolutionize the discovery of drugs for heart disease?

per Bruyneel, Arne A. N., McKeithan, Wesley L., Feyen, Dries A. M., Mercola, Mark
Publicat a Curr Opin Pharmacol (2018)

Cardiomyocyte Specific Deletion of ADAR1 Causes Severe Cardiac Dysfunction and Increased Lethality

per el Azzouzi, Hamid, Vilaça, Andreia P., Feyen, Dries A. M., Gommans, Willemijn M., de Weger, Roel A., Doevendans, Pieter A. F., Sluijter, Joost P. G.
Publicat a Front Cardiovasc Med (2020)

Different types of cultured human adult Cardiac Progenitor Cells have a high degree of transcriptome similarity

per Gaetani, Roberto, Feyen, Dries A M, Doevendans, Pieter A, Gremmels, Hendrik, Forte, Elvira, Fledderus, Joost O, Ramjankhan, Faiz Z, Messina, Elisa, Sussman, Mark A, Giacomello, Alessandro, Sluijter, Joost P G
Publicat a J Cell Mol Med (2014)

SCA1(+) Cells from the Heart Possess a Molecular Circadian Clock and Display Circadian Oscillations in Cellular Functions

per Du Pré, Bastiaan C., Demkes, Evelyne J., Feyen, Dries A.M., Dierickx, Pieterjan, Crnko, Sandra, Kok, Bart J.M., Sluijter, Joost P.G., Doevendans, Pieter A., Vos, Marc A., Van Veen, Toon A.B., Van Laake, Linda W.
Publicat a Stem Cell Reports (2017)

Sustained Delivery of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Stimulates Endogenous Cardiac Repair in the Chronic Infarcted Pig Heart

per Koudstaal, Stefan, Bastings, Maartje M. C., Feyen, Dries A. M., Waring, Cheryl D., van Slochteren, Frebus J., Dankers, Patricia Y. W., Torella, Daniele, Sluijter, Joost P. G., Nadal-Ginard, Bernardo, Doevendans, Pieter A., Ellison, Georgina M., Chamuleau, Steven A. J.
Publicat 2014

Reengineering an antiarrhythmic drug using patient hiPSC-cardiomyocytes to improve therapeutic potential and reduce toxicity

per McKeithan, Wesley L., Feyen, Dries A. M., Bruyneel, Arne A. N., Okolotowicz, Karl J., Ryan, Daniel A., Sampson, Kevin J., Potet, Franck, Savchenko, Alex, Gómez-Galeno, Jorge, Vu, Michelle, Serrano, Ricardo, George, Alfred L., Kass, Robert S., Cashman, John R., Mercola, Mark
Publicat a Cell Stem Cell (2020)

Patient-Specific Induced Pluripotent Stem Cells Implicate Intrinsic Impaired Contractility in Hypoplastic Left Heart Syndrome

per Paige, Sharon L., Galdos, Francisco X., Lee, Soah, Chin, Elizabeth T., Ranjbarvaziri, Sara, Feyen, Dries A.M., Darsha, Adrija K., Xu, Sidra, Ryan, Julia A., Beck, Aimee L., Qureshi, M. Yasir, Miao, Yifei, Gu, Mingxia, Bernstein, Daniel, Nelson, Timothy J., Mercola, Mark, Rabinovitch, Marlene, Ashley, Euan A., Parikh, Victoria N., Wu, Sean M.
Publicat a Circulation (2020)