Engagement of monocytes, NK cells, and CD4(+) Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIV(mac251) vaginal acquisition

The recombinant Canarypox ALVAC-HIV/gp120/alum vaccine regimen was the first to significantly decrease the risk of HIV acquisition in humans, with equal effectiveness in both males and females. Similarly, an equivalent SIV-based ALVAC vaccine regimen decreased the risk of virus acquisition in Indian...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Gorini, Giacomo, Fourati, Slim, Vaccari, Monica, Rahman, Mohammad Arif, Gordon, Shari N., Brown, Dallas R., Law, Lynn, Chang, Jean, Green, Richard, Barrenäs, Fredrik, Liyanage, Namal P. M., Doster, Melvin N., Schifanella, Luca, Bissa, Massimiliano, Silva de Castro, Isabela, Washington-Parks, Robyn, Galli, Veronica, Fuller, Deborah H., Santra, Sampa, Agy, Michael, Pal, Ranajit, Palermo, Robert E., Tomaras, Georgia D., Shen, Xiaoying, LaBranche, Celia C., Montefiori, David C., Venzon, David J., Trinh, Hung V., Rao, Mangala, Gale, Michael, Sekaly, Rafick P., Franchini, Genoveffa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093029/
https://ncbi.nlm.nih.gov/pubmed/32163525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008377
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