Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

The spike (S) protein of severe acute respiratory syndrome (SARS) coronavirus (CoV), a type I transmembrane envelope glycoprotein, consists of S1 and S2 domains responsible for virus binding and fusion, respectively. The S1 contains a receptor-binding domain (RBD) that can specifically bind to angio...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: He, Yuxian, Zhou, Yusen, Liu, Shuwen, Kou, Zhihua, Li, Wenhui, Farzan, Michael, Jiang, Shibo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092904/
https://ncbi.nlm.nih.gov/pubmed/15474494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2004.09.106
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