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VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability
Eukaryotic cellular and most viral RNAs carry a 5′-terminal cap structure, a 5′-5′ triphosphate linkage between the 5′ end of the RNA and a guanosine nucleotide (cap-0). SARS coronavirus (SARS-CoV) nonstructural protein nsp16 functions as a methyltransferase, to methylate mRNA cap-0 structure at the...
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| Publicado no: | Biochem Biophys Res Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7092858/ https://ncbi.nlm.nih.gov/pubmed/25732088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.097 |
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