Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

The 5′-cap structure is a distinct feature of eukaryotic mRNAs, and eukaryotic viruses generally modify the 5′-end of viral RNAs to mimic cellular mRNA structure, which is important for RNA stability, protein translation and viral immune escape. SARS coronavirus (SARS-CoV) encodes two S-adenosyl-L-m...

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Main Authors: Chen, Yu, Su, Ceyang, Ke, Min, Jin, Xu, Xu, Lirong, Zhang, Zhou, Wu, Andong, Sun, Ying, Yang, Zhouning, Tien, Po, Ahola, Tero, Liang, Yi, Liu, Xinqi, Guo, Deyin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192843/
https://ncbi.nlm.nih.gov/pubmed/22022266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002294
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