Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)

In mammals, interleukin (IL)-17A and F are hallmark inflammatory cytokines that play key roles in protection against infection and intestinal mucosal immunity. In the gastrointestinal tract (GI), the induction of antimicrobial peptide (AMP) production via Paneth cells is a fundamental role of IL-17A...

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Foilsithe in:Front Immunol
Main Authors: Okamura, Yo, Morimoto, Natsuki, Ikeda, Daisuke, Mizusawa, Nanami, Watabe, Shugo, Miyanishi, Hiroshi, Saeki, Yuichi, Takeyama, Haruko, Aoki, Takashi, Kinoshita, Masato, Kono, Tomoya, Sakai, Masahiro, Hikima, Jun-ichi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092794/
https://ncbi.nlm.nih.gov/pubmed/32256492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00425
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