Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)

In mammals, interleukin (IL)-17A and F are hallmark inflammatory cytokines that play key roles in protection against infection and intestinal mucosal immunity. In the gastrointestinal tract (GI), the induction of antimicrobial peptide (AMP) production via Paneth cells is a fundamental role of IL-17A...

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Vydáno v:Front Immunol
Hlavní autoři: Okamura, Yo, Morimoto, Natsuki, Ikeda, Daisuke, Mizusawa, Nanami, Watabe, Shugo, Miyanishi, Hiroshi, Saeki, Yuichi, Takeyama, Haruko, Aoki, Takashi, Kinoshita, Masato, Kono, Tomoya, Sakai, Masahiro, Hikima, Jun-ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092794/
https://ncbi.nlm.nih.gov/pubmed/32256492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00425
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