Interleukin-17A/F1 Deficiency Reduces Antimicrobial Gene Expression and Contributes to Microbiome Alterations in Intestines of Japanese medaka (Oryzias latipes)

In mammals, interleukin (IL)-17A and F are hallmark inflammatory cytokines that play key roles in protection against infection and intestinal mucosal immunity. In the gastrointestinal tract (GI), the induction of antimicrobial peptide (AMP) production via Paneth cells is a fundamental role of IL-17A...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Okamura, Yo, Morimoto, Natsuki, Ikeda, Daisuke, Mizusawa, Nanami, Watabe, Shugo, Miyanishi, Hiroshi, Saeki, Yuichi, Takeyama, Haruko, Aoki, Takashi, Kinoshita, Masato, Kono, Tomoya, Sakai, Masahiro, Hikima, Jun-ichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092794/
https://ncbi.nlm.nih.gov/pubmed/32256492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00425
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