Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases

Human neurodegenerative diseases can be characterized as disorders of protein aggregation. As a key player in cellular autophagy and the ubiquitin proteasome system, p62 may represent an effective immunohistochemical target, as well as mechanistic operator, across neurodegenerative proteinopathies....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuropathol Exp Neurol
Prif Awduron: Trejo-Lopez, Jorge A, Sorrentino, Zachary A, Riffe, Cara J, Prokop, Stefan, Dickson, Dennis W, Yachnis, Anthony T, Giasson, Benoit I
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092360/
https://ncbi.nlm.nih.gov/pubmed/32106300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa007
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