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Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases

Human neurodegenerative diseases can be characterized as disorders of protein aggregation. As a key player in cellular autophagy and the ubiquitin proteasome system, p62 may represent an effective immunohistochemical target, as well as mechanistic operator, across neurodegenerative proteinopathies....

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Detalles Bibliográficos
Publicado en:J Neuropathol Exp Neurol
Main Authors: Trejo-Lopez, Jorge A, Sorrentino, Zachary A, Riffe, Cara J, Prokop, Stefan, Dickson, Dennis W, Yachnis, Anthony T, Giasson, Benoit I
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092360/
https://ncbi.nlm.nih.gov/pubmed/32106300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa007
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