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Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors

Gene transfer to airway epithelia with amphotropic pseudotyped retroviral vectors is inefficient following apical vector application. To better understand this inefficiency, we localized the expression of Pit2, the amphotropic receptor, in polarized human airway epithelia. Pit2 was expressed on both...

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Bibliographische Detailangaben
Veröffentlicht in:Gene Ther
Hauptverfasser: Wang, G, Williams, G, Xia, H, Hickey, M, Shao, J, Davidson, BL, McCray, PB
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091907/
https://ncbi.nlm.nih.gov/pubmed/12085240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3301714
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