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Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors

Gene transfer to airway epithelia with amphotropic pseudotyped retroviral vectors is inefficient following apical vector application. To better understand this inefficiency, we localized the expression of Pit2, the amphotropic receptor, in polarized human airway epithelia. Pit2 was expressed on both...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Wang, G, Williams, G, Xia, H, Hickey, M, Shao, J, Davidson, BL, McCray, PB
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7091907/
https://ncbi.nlm.nih.gov/pubmed/12085240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3301714
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