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Oxymatrine Inhibits Proliferation and Migration of Vulvar Squamous Cell Carcinoma Cells via Attenuation of the RAS/RAF/MEK/ERK Pathway

PURPOSE: To evaluate the anti-tumor effects of oxymatrine in vulvar squamous cell carcinoma (VSCC) cells and to explore the underlying mechanisms. METHODS: We selected SW962 and A431 VSCC cell lines. Cell proliferation was examined using MTT assay. Cell cycle and apoptosis were detected using flow c...

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Библиографические подробности
Опубликовано в: :Cancer Manag Res
Главные авторы: Wang, Yanshi, Yang, Shaojie, Zhang, Shanshan, Wu, Xin
Формат: Artigo
Язык:Inglês
Опубликовано: Dove 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090165/
https://ncbi.nlm.nih.gov/pubmed/32256113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S245696
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