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Targeting Cadherin-17 Inactivates Ras/Raf/MEK/ERK Signaling and Inhibits Cell Proliferation in Gastric Cancer

Cadherin-17 (CDH17), one member of 7D-cadherin superfamily, was overexpressed in gastric cancer (GC) and was associated with poor survival, tumor recurrence, metastasis, and advanced tumor stage. So far the cellular function and signaling mechanism of CDH17 in GC remains unclear. In this study, we s...

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Detalhes bibliográficos
Main Authors: Lin, Zhaohu, Zhang, Chao, Zhang, Meifang, Xu, Danqing, Fang, Yanfen, Zhou, Zheng, Chen, Xiaolong, Qin, Ning, Zhang, Xiongwen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896370/
https://ncbi.nlm.nih.gov/pubmed/24465527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085296
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