Targeting Cadherin-17 Inactivates Ras/Raf/MEK/ERK Signaling and Inhibits Cell Proliferation in Gastric Cancer

Cadherin-17 (CDH17), one member of 7D-cadherin superfamily, was overexpressed in gastric cancer (GC) and was associated with poor survival, tumor recurrence, metastasis, and advanced tumor stage. So far the cellular function and signaling mechanism of CDH17 in GC remains unclear. In this study, we s...

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Bibliografski detalji
Glavni autori: Lin, Zhaohu, Zhang, Chao, Zhang, Meifang, Xu, Danqing, Fang, Yanfen, Zhou, Zheng, Chen, Xiaolong, Qin, Ning, Zhang, Xiongwen
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896370/
https://ncbi.nlm.nih.gov/pubmed/24465527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085296
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