CD19(+)CD1d(hi)CD5(hi) B Cells Can Downregulate Malaria ITV Protection by IL-10 Secretion

Infection treatment vaccine (ITV) can lead to sterile protection against malaria infection in mice and humans. However, parasite breakthrough is frequently observed post-challenge. The mechanism of rapid decline in protection after the last immunization is unclear. Herein, C57BL/6 mice were immunize...

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Detalles Bibliográficos
Publicado en:Front Public Health
Main Authors: Guan, Hongli, Peng, Jiacong, Jiang, Liping, Mo, Gang, Li, Xiang, Peng, Xiaohong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Public Health
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090139/
https://ncbi.nlm.nih.gov/pubmed/32257991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpubh.2020.00077
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