PD-1 deficiency promotes TFH cells expansion in ITV-immunized mice by upregulating cytokines secretion

BACKGROUND: T follicular helper (TFH) cells are fundamental for the development of humoral immunity. In our previous study, we found that PD-1 deficiency substantially promoted the expansion of Plasmodium-specific TFH cells and enhanced the humoral immunity of ITV (infection treatment vaccine)-immun...

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Enregistré dans:
Détails bibliographiques
Publié dans:Parasit Vectors
Auteurs principaux: Liu, Taiping, Cheng, Xiangyun, Ding, Yan, Zhu, Feng, Fu, Yong, Peng, Xiaohong, Xu, Wenyue
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035468/
https://ncbi.nlm.nih.gov/pubmed/29980219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-018-2984-4
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