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Upregulated TCRζ improves cytokine secretion in T cells from patients with AML

Previous studies indicated that upregulating TCRζ partially recovers T cell function in patients with leukemia. In this study, we characterized the cytokine profile of TCRζ-transfected T cells from acute myeloid leukemia (AML) patients by Quantibody®Array Glass Chip. Firstly, the significantly lower...

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Podrobná bibliografie
Vydáno v:J Hematol Oncol
Hlavní autoři: Chen, Shaohua, Zha, Xianfeng, Shi, Li, Zhou, Lingling, Yang, Lijian, Li, Bo, Wu, Xiuli, Zhong, Jun, Zhang, Tao, Lu, Yuhong, Zhu, Kanger, Li, Yangqiu
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488036/
https://ncbi.nlm.nih.gov/pubmed/26081440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0170-0
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