Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) crossing and brain infection in mice. We use a brain infectivity assay to screen signature-tagged mutagenesis (STM)-based li...

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Vydáno v:Nat Commun
Hlavní autoři: Lee, Kyung-Tae, Hong, Joohyeon, Lee, Dong-Gi, Lee, Minjae, Cha, Suyeon, Lim, Yu-Gyeong, Jung, Kwang-Woo, Hwangbo, Areum, Lee, Yelin, Yu, Shang-Jie, Chen, Ying-Lien, Lee, Jong-Seung, Cheong, Eunji, Bahn, Yong-Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090016/
https://ncbi.nlm.nih.gov/pubmed/32251295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15329-2
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