Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) crossing and brain infection in mice. We use a brain infectivity assay to screen signature-tagged mutagenesis (STM)-based li...

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Pubblicato in:Nat Commun
Autori principali: Lee, Kyung-Tae, Hong, Joohyeon, Lee, Dong-Gi, Lee, Minjae, Cha, Suyeon, Lim, Yu-Gyeong, Jung, Kwang-Woo, Hwangbo, Areum, Lee, Yelin, Yu, Shang-Jie, Chen, Ying-Lien, Lee, Jong-Seung, Cheong, Eunji, Bahn, Yong-Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090016/
https://ncbi.nlm.nih.gov/pubmed/32251295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15329-2
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