Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) crossing and brain infection in mice. We use a brain infectivity assay to screen signature-tagged mutagenesis (STM)-based li...

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Publié dans:Nat Commun
Auteurs principaux: Lee, Kyung-Tae, Hong, Joohyeon, Lee, Dong-Gi, Lee, Minjae, Cha, Suyeon, Lim, Yu-Gyeong, Jung, Kwang-Woo, Hwangbo, Areum, Lee, Yelin, Yu, Shang-Jie, Chen, Ying-Lien, Lee, Jong-Seung, Cheong, Eunji, Bahn, Yong-Sun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090016/
https://ncbi.nlm.nih.gov/pubmed/32251295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15329-2
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