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Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans

Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) crossing and brain infection in mice. We use a brain infectivity assay to screen signature-tagged mutagenesis (STM)-based li...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Kyung-Tae, Hong, Joohyeon, Lee, Dong-Gi, Lee, Minjae, Cha, Suyeon, Lim, Yu-Gyeong, Jung, Kwang-Woo, Hwangbo, Areum, Lee, Yelin, Yu, Shang-Jie, Chen, Ying-Lien, Lee, Jong-Seung, Cheong, Eunji, Bahn, Yong-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7090016/
https://ncbi.nlm.nih.gov/pubmed/32251295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15329-2
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