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Distinct and Redundant Roles of Protein Tyrosine Phosphatases Ptp1 and Ptp2 in Governing the Differentiation and Pathogenicity of Cryptococcus neoformans

Protein tyrosine phosphatases (PTPs) serve as key negative-feedback regulators of mitogen-activated protein kinase (MAPK) signaling cascades. However, their roles and regulatory mechanisms in human fungal pathogens remain elusive. In this study, we characterized the functions of two PTPs, Ptp1 and P...

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Autori principali: Lee, Kyung-Tae, Byun, Hyo-Jeong, Jung, Kwang-Woo, Hong, Joohyeon, Cheong, Eunji, Bahn, Yong-Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054275/
https://ncbi.nlm.nih.gov/pubmed/24728196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00069-14
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