Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis; however, treatment options remain limited. Here we report the construction of 264 signature-tagged gene-deletion strains for 129 putative kinases, and examine their phenotypic traits under 30 distinct in vitro growt...

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Published in:Nat Commun
Main Authors: Lee, Kyung-Tae, So, Yee-Seul, Yang, Dong-Hoon, Jung, Kwang-Woo, Choi, Jaeyoung, Lee, Dong-Gi, Kwon, Hyojeong, Jang, Juyeong, Wang, Li Li, Cha, Soohyun, Meyers, Gena Lee, Jeong, Eunji, Jin, Jae-Hyung, Lee, Yeonseon, Hong, Joohyeon, Bang, Soohyun, Ji, Je-Hyun, Park, Goun, Byun, Hyo-Jeong, Park, Sung Woo, Park, Young-Min, Adedoyin, Gloria, Kim, Taeyup, Averette, Anna F., Choi, Jong-Soon, Heitman, Joseph, Cheong, Eunji, Lee, Yong-Hwan, Bahn, Yong-Sun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052723/
https://ncbi.nlm.nih.gov/pubmed/27677328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12766
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