Differential effect of lacosamide on Na(v)1.7 variants from responsive and non-responsive patients with small fibre neuropathy

Small fibre neuropathy is a common pain disorder, which in many cases fails to respond to treatment with existing medications. Gain-of-function mutations of voltage-gated sodium channel Na(v)1.7 underlie dorsal root ganglion neuronal hyperexcitability and pain in a subset of patients with small fibr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Brain
Main Authors: Labau, Julie I R, Estacion, Mark, Tanaka, Brian S, de Greef, Bianca T A, Hoeijmakers, Janneke G J, Geerts, Margot, Gerrits, Monique M, Smeets, Hubert J M, Faber, Catharina G, Merkies, Ingemar S J, Lauria, Giuseppe, Dib-Hajj, Sulayman D, Waxman, Stephen G
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089662/
https://ncbi.nlm.nih.gov/pubmed/32011655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados