Cross-linked Small Polyethylenimines: While Still Nontoxic, Deliver DNA Efficiently to Mammalian Cells in Vitro and in Vivo

PURPOSE. Polyethylenimine (PEI) is among the most efficient nonviral gene delivery vectors. Its efficiency and cytotoxicity depend on molecular weight, with the 25-kDa PEI being most efficient but cytotoxic. Smaller PEIs are noncytotoxic but less efficient. Enhancement in gene delivery efficiency wi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharm Res
Prif Awduron: Thomas, Mini, Ge, Qing, Lu, James J., Chen, Jianzhu, Klibanov, Alexander
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Kluwer Academic Publishers-Plenum Publishers 2005
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089549/
https://ncbi.nlm.nih.gov/pubmed/15835742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-004-1874-y
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