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Conjugation to gold nanoparticles enhances polyethylenimine's transfer of plasmid DNA into mammalian cells

Branched polyethylenimine (PEI) chains with an average molecular mass of 2 kDa (PEI2) have been covalently attached to gold nanoparticles (GNPs), and the potency of the resulting PEI2–GNPs conjugates as vectors for the delivery of plasmid DNA into monkey kidney (COS-7) cells in the presence of serum...

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Detalhes bibliográficos
Main Authors: Thomas, Mini, Klibanov, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC170885/
https://ncbi.nlm.nih.gov/pubmed/12886020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1233634100
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