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Conjugation to gold nanoparticles enhances polyethylenimine's transfer of plasmid DNA into mammalian cells

Branched polyethylenimine (PEI) chains with an average molecular mass of 2 kDa (PEI2) have been covalently attached to gold nanoparticles (GNPs), and the potency of the resulting PEI2–GNPs conjugates as vectors for the delivery of plasmid DNA into monkey kidney (COS-7) cells in the presence of serum...

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Autors principals: Thomas, Mini, Klibanov, Alexander M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC170885/
https://ncbi.nlm.nih.gov/pubmed/12886020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1233634100
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