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Molecular Signatures of Fusion Proteins in Cancer

[Image: see text] Although gene fusions are recognized as driver mutations in a wide variety of cancers, the general molecular mechanisms underlying oncogenic fusion proteins are insufficiently understood. Here, we employ large-scale data integration and machine learning and (1) identify three funct...

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Publicado en:ACS Pharmacol Transl Sci
Main Authors: Latysheva, Natasha S., Babu, M. Madan
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2019
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088938/
https://ncbi.nlm.nih.gov/pubmed/32219217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00019
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