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Molecular Pathways - ROS1 Fusion Proteins in Cancer
Genetic alterations that lead to constitutive activation of kinases are frequently observed in cancer. In many cases, the growth and survival of tumor cells relies upon an activated kinase such that inhibition of its activity is an effective anti-cancer therapy. ROS1 is a receptor tyrosine kinase th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732549/ https://ncbi.nlm.nih.gov/pubmed/23719267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2851 |
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