Discovery of novel low-molecular-weight HIV-1 inhibitors interacting with cyclophilin A using in silico screening and biological evaluations

Cyclophilin A has attracted attention recently as a new target of anti-human immunodeficiency virus type 1 (HIV-1) drugs. However, so far no drug against HIV-1 infection exhibiting this mechanism of action has been approved. To identify new potent candidates for inhibitors, we performed in silico sc...

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Bibliographic Details
Published in:J Mol Model
Main Authors: Tian, Yu-Shi, Verathamjamras, Chris, Kawashita, Norihito, Okamoto, Kousuke, Yasunaga, Teruo, Ikuta, Kazuyoshi, Kameoka, Masanori, Takagi, Tatsuya
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2012
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088282/
https://ncbi.nlm.nih.gov/pubmed/22949064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-012-1560-7
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