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MG132-mediated inhibition of the ubiquitin–proteasome pathway ameliorates cancer cachexia
PURPOSE: To evaluate the effect of proteasome inhibitor MG132 in cancer cachexia and to delineate the molecular mechanism underlying. METHODS: We established an experimental cancer cachexia model by subcutaneously implanting colon 26 cells into the armpits of BALB/c mice. Following administration of...
Gespeichert in:
| Veröffentlicht in: | J Cancer Res Clin Oncol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer-Verlag
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7087863/ https://ncbi.nlm.nih.gov/pubmed/23535871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-013-1412-6 |
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