Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia

Muscle protein degradation is thought to play a major role in muscle atrophy in cancer cachexia. To investigate the importance of the ubiquitin-proteasome pathway, which has been suggested to be the main degradative pathway mediating progressive protein loss in cachexia, the expression of mRNA for p...

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Bibliographic Details
Main Authors: Khal, J, Wyke, S M, Russell, S T, Hine, A V, Tisdale, M J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2005
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361629/
https://ncbi.nlm.nih.gov/pubmed/16160695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602780
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