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Aptameric enzyme subunit for homogeneous DNA sensing

We have developed an aptameric enzyme subunit (AES) which can detect the DNA in a homogeneous solution. The AES is an artificial enzyme subunit composed of an enzyme-inhibiting aptamer bearing a target-molecule binding site. We connected a probe DNA to a thrombin-inhibiting aptamer at its 5′ or 3′ e...

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Bibliographic Details
Published in:Biotechnol Lett
Main Authors: Ikebukuro, Kazunori, Yoshida, Wataru, Sode, Koji
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7087721/
https://ncbi.nlm.nih.gov/pubmed/17849085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10529-007-9526-z
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