Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1

Rationale: Cardiac fibrosis is an integral constituent of every form of chronic heart disease, and persistence of fibrosis reduces tissue compliance and accelerates the progression to heart failure. Relaxin-2 is a human hormone, which has various physiological functions such as mediating renal vasod...

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Foilsithe in:Theranostics
Main Authors: Wilhelmi, Tim, Xu, Xingbo, Tan, Xiaoying, Hulshoff, Melanie S., Maamari, Sabine, Sossalla, Samuel, Zeisberg, Michael, Zeisberg, Elisabeth M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ivyspring International Publisher 2020
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7086357/
https://ncbi.nlm.nih.gov/pubmed/32226528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38640
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