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DNMT1 and HDAC2 Cooperate to Facilitate Aberrant Promoter Methylation in Inorganic Phosphate-Induced Endothelial-Mesenchymal Transition

While phosphorus in the form of inorganic or organic phosphate is critically involved in most cellular functions, high plasma levels of inorganic phosphate levels have emerged as independent risk factor for cardiac fibrosis, cardiovascular morbidity and decreased life-expectancy. While the link of h...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tan, Xiaoying, Xu, Xingbo, Zeisberg, Michael, Zeisberg, Elisabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729486/
https://ncbi.nlm.nih.gov/pubmed/26815200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147816
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