Genetic and regulatory architecture of Alzheimer's disease in the APOE region

INTRODUCTION: Apolipoprotein E (APOE) ε2 and ε4 alleles encoded by rs7412 and rs429358 polymorphisms, respectively, are landmark contra and pro “risk” factors for Alzheimer's disease (AD). METHODS: We examined differences in linkage disequilibrium (LD) structures between (1) AD‐affected and una...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Kulminski, Alexander M., Shu, Leonardo, Loika, Yury, He, Liang, Nazarian, Alireza, Arbeev, Konstantin, Ukraintseva, Svetlana, Yashin, Anatoliy, Culminskaya, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085286/
https://ncbi.nlm.nih.gov/pubmed/32211503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12008
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