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Amyloid duration is associated with preclinical cognitive decline and tau PET

INTRODUCTION: This study applies a novel algorithm to longitudinal amyloid positron emission tomography (PET) imaging to identify age‐heterogeneous amyloid trajectory groups, estimate the age and duration (chronicity) of amyloid positivity, and investigate chronicity in relation to cognitive decline...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Koscik, Rebecca L., Betthauser, Tobey J., Jonaitis, Erin M., Allison, Samantha L., Clark, Lindsay R., Hermann, Bruce P., Cody, Karly A., Engle, Jonathan W., Barnhart, Todd E., Stone, Charles K., Chin, Nathaniel A., Carlsson, Cynthia M., Asthana, Sanjay, Christian, Bradley T., Johnson, Sterling C.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085284/
https://ncbi.nlm.nih.gov/pubmed/32211502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12007
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