Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease

INTRODUCTION: This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) diagnosis, its association with amyloid and tau pathology, as well as its potential to predict brain atrophy, cognition, and amyloid accumulation. METHODS: CSF NfL co...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Dhiman, Kunal, Gupta, Veer Bala, Villemagne, Victor L., Eratne, Dhamidhu, Graham, Petra L., Fowler, Christopher, Bourgeat, Pierrick, Li, Qiao‐Xin, Collins, Steven, Bush, Ashley I., Rowe, Christopher C., Masters, Colin L., Ames, David, Hone, Eugene, Blennow, Kaj, Zetterberg, Henrik, Martins, Ralph N.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Cerebrospinal Fluid Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085283/
https://ncbi.nlm.nih.gov/pubmed/32211500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12005
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