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Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

INTRODUCTION: Several blood‐based biomarkers are associated with neuronal injury, but their utility in interventional clinical trials is unclear. This study retrospectively evaluated the utility of plasma neurofilament light (NfL) and total tau (t‐tau) in an 18‐month trial in mild Alzheimer's d...

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Bibliographic Details
Published in:Alzheimers Dement (Amst)
Main Authors: Raket, Lars Lau, Kühnel, Line, Schmidt, Ellen, Blennow, Kaj, Zetterberg, Henrik, Mattsson‐Carlgren, Niklas
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507310/
https://ncbi.nlm.nih.gov/pubmed/32995466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12099
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