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Utility of plasma neurofilament light and total tau for clinical trials in Alzheimer's disease

INTRODUCTION: Several blood‐based biomarkers are associated with neuronal injury, but their utility in interventional clinical trials is unclear. This study retrospectively evaluated the utility of plasma neurofilament light (NfL) and total tau (t‐tau) in an 18‐month trial in mild Alzheimer's d...

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Publicado en:Alzheimers Dement (Amst)
Autores principales: Raket, Lars Lau, Kühnel, Line, Schmidt, Ellen, Blennow, Kaj, Zetterberg, Henrik, Mattsson‐Carlgren, Niklas
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507310/
https://ncbi.nlm.nih.gov/pubmed/32995466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12099
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