Cerebrospinal fluid neurofilament light concentration predicts brain atrophy and cognition in Alzheimer's disease

INTRODUCTION: This study assessed the utility of cerebrospinal fluid (CSF) neurofilament light (NfL) in Alzheimer's disease (AD) diagnosis, its association with amyloid and tau pathology, as well as its potential to predict brain atrophy, cognition, and amyloid accumulation. METHODS: CSF NfL co...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Dhiman, Kunal, Gupta, Veer Bala, Villemagne, Victor L., Eratne, Dhamidhu, Graham, Petra L., Fowler, Christopher, Bourgeat, Pierrick, Li, Qiao‐Xin, Collins, Steven, Bush, Ashley I., Rowe, Christopher C., Masters, Colin L., Ames, David, Hone, Eugene, Blennow, Kaj, Zetterberg, Henrik, Martins, Ralph N.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Cerebrospinal Fluid Biomarkers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085283/
https://ncbi.nlm.nih.gov/pubmed/32211500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12005
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