Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

Our previous studies indicated that phosphoinositide specific phospholipase Cγ1 (PLCγ1) was involved in autophagy induction in colon and hepatic carcinoma cells. However, whether and how PLCγ1 regulation in human lung adenocarcinoma is linked to autophagy remains unclear. Here, we assessed the prote...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Biol Sci
Auteurs principaux: Lu, Xiaohong, Fu, Haijing, Chen, Rui, Wang, Yue, Zhan, Yanyan, Song, Gang, Hu, Tianhui, Xia, Chun, Tian, Xuemei, Zhang, Bing
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085223/
https://ncbi.nlm.nih.gov/pubmed/32210730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.42962
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