Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells

Phosphoinositide-specific phospholipase C (PLC) γ1 has been reported to be involved in cancer cell proliferation and metastasis. However, whether PLCγ1 modulates autophagy and the underlying mechanism remains unclear. Here, we investigated the relationship between PLCγ1 and autophagy in the human co...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dai, Lianzhi, Chen, Xiaolei, Lu, Xiaohong, Wang, Fen, Zhan, Yanyan, Song, Gang, Hu, Tianhui, Xia, Chun, Zhang, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654964/
https://ncbi.nlm.nih.gov/pubmed/29066806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13334-y
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