Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro

Our previous studies indicated that phosphoinositide specific phospholipase Cγ1 (PLCγ1) was involved in autophagy induction in colon and hepatic carcinoma cells. However, whether and how PLCγ1 regulation in human lung adenocarcinoma is linked to autophagy remains unclear. Here, we assessed the prote...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Lu, Xiaohong, Fu, Haijing, Chen, Rui, Wang, Yue, Zhan, Yanyan, Song, Gang, Hu, Tianhui, Xia, Chun, Tian, Xuemei, Zhang, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7085223/
https://ncbi.nlm.nih.gov/pubmed/32210730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.42962
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