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Dynamical Effects of Trimethylamine N-Oxide on Aqueous Solutions of Urea
Trimethylamine N-oxide (TMAO) stabilizes protein structures, whereas urea destabilizes proteins, and their opposing effects can be counteracted at a 1:2 ratio of TMAO to urea. To investigate how they affect solution dynamics, molecular dynamics simulations have been carried out for aqueous solutions...
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| 發表在: | J Phys Chem B |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7085122/ https://ncbi.nlm.nih.gov/pubmed/30638025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b09874 |
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