Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice

Background: Glaucoma is an optic neuropathy and involves the progressive degeneration of retinal ganglion cells (RGCs), which leads to blindness in patients. We investigated the role of the neuroprotective kynurenic acid (KYNA) in RGC death against retinal ischemia/reperfusion (I/R) injury. Methods:...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Nahomi, Rooban B., Nam, Mi-Hyun, Rankenberg, Johanna, Rakete, Stefan, Houck, Julie A., Johnson, Ginger C., Stankowska, Dorota L., Pantcheva, Mina B., MacLean, Paul S., Nagaraj, Ram H.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084183/
https://ncbi.nlm.nih.gov/pubmed/32151061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051795
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