Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization

Enormous progress has been made in global efforts to eradicate poliovirus, using live-attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to wild poliovirus has declined, vaccine-derived poliovirus (VDPV) has emerged in areas of low-vaccine coverage. Coordinated...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Konopka-Anstadt, Jennifer L., Campagnoli, Ray, Vincent, Annelet, Shaw, Jing, Wei, Ling, Wynn, Nhien T., Smithee, Shane E., Bujaki, Erika, Te Yeh, Ming, Laassri, Majid, Zagorodnyaya, Tatiana, Weiner, Amy J., Chumakov, Konstantin, Andino, Raul, Macadam, Andrew, Kew, Olen, Burns, Cara C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083942/
https://ncbi.nlm.nih.gov/pubmed/32218998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0176-7
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