Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization

Enormous progress has been made in global efforts to eradicate poliovirus, using live-attenuated Sabin oral poliovirus vaccine (OPV). However, as the incidence of disease due to wild poliovirus has declined, vaccine-derived poliovirus (VDPV) has emerged in areas of low-vaccine coverage. Coordinated...

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Dades bibliogràfiques
Publicat a:NPJ Vaccines
Autors principals: Konopka-Anstadt, Jennifer L., Campagnoli, Ray, Vincent, Annelet, Shaw, Jing, Wei, Ling, Wynn, Nhien T., Smithee, Shane E., Bujaki, Erika, Te Yeh, Ming, Laassri, Majid, Zagorodnyaya, Tatiana, Weiner, Amy J., Chumakov, Konstantin, Andino, Raul, Macadam, Andrew, Kew, Olen, Burns, Cara C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083942/
https://ncbi.nlm.nih.gov/pubmed/32218998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0176-7
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