Modulation of Poliovirus Replicative Fitness in HeLa Cells by Deoptimization of Synonymous Codon Usage in the Capsid Region

We replaced degenerate codons for nine amino acids within the capsid region of the Sabin type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons. Codon replacements were introduced into four contiguous intervals spanning 97% of the capsid region. In the capsid region...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Burns, Cara Carthel, Shaw, Jing, Campagnoli, Ray, Jorba, Jaume, Vincent, Annelet, Quay, Jacqueline, Kew, Olen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Genetic Diversity and Evolution
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440415/
https://ncbi.nlm.nih.gov/pubmed/16537593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3259-3272.2006
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak