Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses

The mode of action for oncolytic viruses (OVs) in cancer treatment is thought to depend on a direct initial cytotoxic effect against infected tumor cells and subsequent activation of immune cell responses directed against the neoplasm. To study both of these effects in a mouse model of glioblastoma...

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Vydáno v:Sci Rep
Hlavní autoři: Alayo, Quazim A., Ito, Hirotaka, Passaro, Carmela, Zdioruk, Mykola, Mahmoud, Ahmad Bakur, Grauwet, Korneel, Zhang, Xiaoli, Lawler, Sean E., Reardon, David A., Goins, William F., Fernandez, Soledad, Chiocca, E. Antonio, Nakashima, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083912/
https://ncbi.nlm.nih.gov/pubmed/32198420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61736-2
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