Glioblastoma infiltration of both tumor- and virus-antigen specific cytotoxic T cells correlates with experimental virotherapy responses

The mode of action for oncolytic viruses (OVs) in cancer treatment is thought to depend on a direct initial cytotoxic effect against infected tumor cells and subsequent activation of immune cell responses directed against the neoplasm. To study both of these effects in a mouse model of glioblastoma...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Alayo, Quazim A., Ito, Hirotaka, Passaro, Carmela, Zdioruk, Mykola, Mahmoud, Ahmad Bakur, Grauwet, Korneel, Zhang, Xiaoli, Lawler, Sean E., Reardon, David A., Goins, William F., Fernandez, Soledad, Chiocca, E. Antonio, Nakashima, Hiroshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083912/
https://ncbi.nlm.nih.gov/pubmed/32198420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61736-2
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