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Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells
The Escherichia coli transcription-repair coupling factor Mfd displaces stalled RNA polymerase and delivers the stall site to the nucleotide excision repair factors UvrAB for damage detection. Whether this handoff from RNA polymerase to UvrA occurs via the Mfd-UvrA(2)-UvrB complex or alternate react...
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| Publicat a: | Nat Commun |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083905/ https://ncbi.nlm.nih.gov/pubmed/32198374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15182-3 |
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