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Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells
The Escherichia coli transcription-repair coupling factor Mfd displaces stalled RNA polymerase and delivers the stall site to the nucleotide excision repair factors UvrAB for damage detection. Whether this handoff from RNA polymerase to UvrA occurs via the Mfd-UvrA(2)-UvrB complex or alternate react...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083905/ https://ncbi.nlm.nih.gov/pubmed/32198374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15182-3 |
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