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The transcription-repair coupling factor Mfd associates with RNA polymerase in the absence of exogenous damage

During transcription elongation, bacterial RNA polymerase (RNAP) can pause, backtrack or stall when transcribing template DNA. Stalled transcription elongation complexes at sites of bulky lesions can be rescued by the transcription terminator Mfd. The molecular mechanisms of Mfd recruitment to trans...

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Publicado en:Nat Commun
Main Authors: Ho, Han N., van Oijen, Antoine M., Ghodke, Harshad
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910403/
https://ncbi.nlm.nih.gov/pubmed/29679003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03790-z
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